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Levothyroxine sodium

CAS No. 55-03-8

Levothyroxine sodium ( L-T4 sodium,L-Thyroxine sodium,LT4 sodium )

产品货号. M22952 CAS No. 55-03-8

Levothyroxine, the major hormone derived from the thyroid gland, is the agonist of Thyroid hormone receptor alpha and beta.evothyroxine (L-T(4))can upregulate the expression of P-gp mRNA and protein in LS180 cells, but only L-T(4) and L-T(3) can produce the same effect in Caco-2 cells, which are relatively lacking in PXR.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
500MG ¥381 有现货
1G ¥502 有现货

生物学信息

  • 产品名称
    Levothyroxine sodium
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Levothyroxine, the major hormone derived from the thyroid gland, is the agonist of Thyroid hormone receptor alpha and beta.evothyroxine (L-T(4))can upregulate the expression of P-gp mRNA and protein in LS180 cells, but only L-T(4) and L-T(3) can produce the same effect in Caco-2 cells, which are relatively lacking in PXR.
  • 产品描述
    Levothyroxine, the major hormone derived from the thyroid gland, is the agonist of Thyroid hormone receptor alpha and beta.evothyroxine (L-T(4))can upregulate the expression of P-gp mRNA and protein in LS180 cells, but only L-T(4) and L-T(3) can produce the same effect in Caco-2 cells, which are relatively lacking in PXR.
  • 同义词
    L-T4 sodium,L-Thyroxine sodium,LT4 sodium
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Thyroid Hormone
  • 研究领域
    Endocrine system
  • 适应症
    Hypothyroidism

化学信息

  • CAS Number
    55-03-8
  • 分子量
    798.85
  • 分子式
    C15H10I4NO4.Na
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:100 mg/ml (125.18 mM)
  • SMILES
    N[C@@H](CC1=CC(I)=C(OC2=CC(I)=C(O)C(I)=C2)C(I)=C1)C(O[Na])=O
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Mitin T, et al. Drug Metab Dispos. 2004, 32(8):779-82.
产品手册
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