Levothyroxine sodium ( L-T4 sodium,L-Thyroxine sodium,LT4 sodium )

产品货号. M22952 CAS No. 55-03-8

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Levothyroxine sodium
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

左甲状腺素是来自甲状腺的主要激素，是甲状腺激素受体α和β的激动剂。左甲状腺素(LT(4))可以上调LS180细胞中P-gp mRNA和蛋白的表达，但仅LT(4) LT(3)可以在PXR相对缺乏的Caco-2细胞中产生相同的效果。
产品描述

Levothyroxine, the major hormone derived from the thyroid gland, is the agonist of Thyroid hormone receptor alpha and beta.evothyroxine (L-T(4))can upregulate the expression of P-gp mRNA and protein in LS180 cells, but only L-T(4) and L-T(3) can produce the same effect in Caco-2 cells, which are relatively lacking in PXR.
体外实验

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体内实验

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同义词

L-T4 sodium,L-Thyroxine sodium,LT4 sodium
通路

Others
靶点

Other Targets
受体

Thyroid Hormone
研究领域

Endocrine system
适应症

Hypothyroidism

1. Mitin T, et al. Drug Metab Dispos. 2004, 32(8):779-82.

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